TCRP联合左炔诺孕酮宫内节育系统治疗子宫内膜息肉所致异常子宫出血的应用价值
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1.太康县人民医院;2.河南科技大学第一附属医院

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二0二五年度河南省医学科技攻关计划项目(LHGJ20250561)。


The application value of of TCRP combined with levonorgestrel-releasing intrauterine system in treating abnormal uterine bleeding caused by endometrial polyp
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1.Taikang County People''s Hospital;2.The First Affiliated Hospital of Henan University of Science and Technology‌

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    摘要:

    目的 探讨宫腔镜子宫内膜息肉切除术(transcervical resection of polyp,TCRP)联合左炔诺孕酮宫内节育系统(levonorgestrel-releasing intrauterine system,LNG-IUS)治疗子宫内膜息肉(endometrial polyp,EP)所致异常子宫出血(abnormal uterine bleeding,AUB)的临床价值。方法 选取2022年6月至2025年6月太康县人民医院收治的80例EP合并AUB患者的临床资料,根据干预方案不同分为对照组(n=40,单纯TCRP手术)和联合组(n=40,TCRP+术后即时放置LNG-IUS),随访至术后12个月。同时比较两组月经量[月经失血图(pictorial blood loss assessment chart,PBAC)评分]、血红蛋白(hemoglobin,Hb)水平、子宫内膜厚度、息肉复发率及不良反应发生情况。结果 术后12个月,联合组PBAC评分显著低于对照组(P<0.05),Hb水平显著高于对照组(P<0.05);联合组子宫内膜厚度显著薄于对照组(P<0.05),息肉复发率显著低于对照组(P<0.05)。两组均无LNG-IUS穿孔、脱落或严重感染发生。结论 TCRP联合LNG-IUS可有效减少EP患者术后月经量、改善贫血状态、抑制内膜增生并降低息肉复发率,二者联合干预具有协同增效作用。

    Abstract:

    Objective To explore the clinical value of hysteroscopic transcervical resection of polyp (TCRP) combined with levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of abnormal uterine bleeding (AUB) caused by endometrial polyp (EP). Methods The clinical data of 80 patients with EP complicated by AUB admitted to Taikang County People’s Hospital from June 2022 to June 2025 were selected. According to the different intervention plans, they were divided into the control group (n=40, undergoing TCRP surgery alone) and the combined group (n=40, TCRP+immediate postoperative LNG-IUS placement). The follow-up was conducted until 12 months after the surgery. At the same time, the menstrual flow [pictorial blood loss assessment chart (PBAC) score], hemoglobin (Hb) level, endometrial thickness, polyp recurrence rate and adverse reactions were compared between the two groups. Results At 12 months after operation, the PBAC score in the combined group was significantly lower than that in the control group (P< 0.05), the Hb level in the combined group was significantly higher than that in the control group (P<0.05), the endometrial thickness in the combined group was significantly thinner than that in the control group (P<0.05), and the polyp recurrence rate in the combined group was significantly lower than that in the control group (P<0.05). No LNG-IUS perforation, detachment or severe infection occurred in either group. Conclusion TCRP combined with LNG-IUS can effectively reduce postoperative menstrual flow, improve anemia, inhibit endometrial hyperplasia and reduce recurrence rate in patients with endometrial polyps. The combined intervention of the two has a synergistic effect.

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司莹丽,姜颖显,黄鹏翀,吴忱莼. TCRP联合左炔诺孕酮宫内节育系统治疗子宫内膜息肉所致异常子宫出血的应用价值[J].生物医学工程学进展,2026,(4):246-249

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  • 收稿日期:2026-07-30
  • 最后修改日期:2026-08-03
  • 录用日期:2026-08-07
  • 在线发布日期: 2026-10-20
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