Objective To investigate the efficacy of phloroglucinol combined with oxytocin in promoting labor progress in parturients with arrested active phase labor. Methods A total of 86 parturients with arrested active phase labor admitted to Huaxian People’s Hospital, Henan Province from May 2024 to May 2025 were selected and, according to the randomized controlled principle, divided into control group (receiving oxytocin) and study group (receiving phloroglucinol＋oxytocin), 43 cases in each group. Indicators regarding cervical maturity, duration of labor stages, amount of intrapartum bleeding, severity of labor pain, adverse delivery outcomes, and adverse reactions were compared between the two groups. Results After treatment, compared with the control group, the study group showed a higher Bishop cervical score, a shorter duration of labor stages, less intrapartum bleeding, and a lower VAS score (all P＜0.05). The incidence of adverse delivery outcomes in the study group was lower than that in the control group (P＜0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05). Conclusion The combination of phloroglucinol and oxytocin can improve cervical maturity in parturients with arrested active phase labor, shorten the duration of labor stages, reduce intrapartum bleeding and labor pain, lower the risk of adverse delivery outcomes, without increasing adverse reactions.