DCE-MRI联合不同b值弥散加权成像对宫颈癌术前分期的诊断价值
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河南科技大学第一附属医院

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Diagnostic value of DCE-MRI combined with diffusion-weighted imaging using various b-values for preoperative staging of cervical cancer
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The First Affiliated Hospital of Henan University of Science and Technology

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    摘要:

    目的 探讨动态增强磁共振成像(dynamic contrast-enhanced magnetic resonance imaging,DCE-MRI)联合不同扩散敏感梯度(diffusion-sensitizing gradient, DSG)值(b值)弥散加权成像(diffusion-weighted imaging,DWI)对宫颈癌术前分期的诊断价值。方法 回顾性选取2020 年3 月至2024 年4 月本院收治的92 例宫颈癌患者为研究对象。所有患者均接受DCE-MRI及DWI检查,对比不同国际妇产科联盟(International Federation of Gynecology and Obstetrics,FIGO)分期患者的DCE-MRI定量参数[容量转移常数(volume transfer constant,Ktrans)、速率常数(rate constant,Kep)、血管外细胞外间隙容积分数(extravascular extracellular space volume fraction,Ve)]和表观扩散系数(apparent diffusion coefficient,ADC)。以手术病理结果为金标准,比较DCE-MRI、DWI及两者联合对宫颈癌分期的诊断符合率。结果 随着FIGO分期的升高,Ktrans、Kep、Ve 值均呈升高趋势(均P<0.05),ADC值则呈下降趋势(P<0.05)。DCE-MRI与手术病理分期的总体诊断符合率为88.04%(81/92),DWI为89.13%(82/92),两者联合诊断符合率达96.74%(89/92),显著高于两种单一检查方法(P<0.05)。结论 DCE-MRI定量参数与不同b值DWI检查均能有效辅助宫颈癌术前分期诊断,且两者联合可显著提高分期诊断的准确性,具有较高的临床推广价值。

    Abstract:

    Objective To evaluate the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) combined with diffusion-weighted imaging (DWI) using various diffusion-sensitive gradient (DSG) value (b-values) for the preoperative staging of cervical cancer. Methods A retrospective study was conducted on 92 patients with cervical cancer admitted to our hospital from March 2020 to April 2024. All patients underwent both DCE-MRI and DWI examinations. The DCE-MRI quantitative parameters [volume transfer constant (Ktrans), rate constant (Kep), and extravascular extracellular space volume fraction (Ve)] and apparent diffusion coefficient (ADC) values were compared across different stages defined by the International Federation of Gynecology and Obstetrics (FIGO). Using surgical and pathological findings as the gold standard, the diagnostic accuracy of DCE-MRI, DWI, and their combination for cervical cancer staging was compared. Results As FIGO stages progressed, the values of Ktrans, Kep, and Ve exhibited an increasing trend (all P<0.05), while ADC values showed a decreasing trend (P<0.05). The overall diagnostic accuracy of DCE-MRI for staging was 88.04% (81/92), and that of DWI was 89.13% (82/92). However, the combined diagnostic accuracy reached 96.74% (89/92), which was significantly higher than that of either modality alone (P<0.05). Conclusion Both DCE-MRI quantitative parameters and DWI with various b-values are effective auxiliary tools for the preoperative staging of cervical cancer. Their combination significantly enhances diagnostic accuracy and has high clinical application value.

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王轩轩. DCE-MRI联合不同b值弥散加权成像对宫颈癌术前分期的诊断价值[J].生物医学工程学进展,2026,(1):69-73

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  • 收稿日期:2025-12-26
  • 最后修改日期:2026-01-28
  • 录用日期:2026-01-28
  • 在线发布日期: 2026-04-14
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