GDS-15 评分、MFS 评分、PSQI 评分与HbA1c 对老年2 型糖尿病合并高血压患者认知衰弱的预测价值
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漯河市立医院(漯河医专二附院)

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漯河医学高等专科学校科技创新项目(SKCXYFY20240)。


The predictive value of GDS-15 score, MFS score, PSQI score and HbA1c for cognitive decline in elderly patients with type 2 diabetes mellitus complicated with hypertension
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Luohe Municipal Hospital(The Second Affiliated Hospital of Luohe Medical College)

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    目的 分析简化版老年抑郁量表15(15-item geriatric depression scale,GDS-15)评分、中文版Morse跌倒评估量表(Morse fall scale,MFS)评分、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评分与糖化血红蛋白(glycated hemoglobin A1c,HbA1c)对老年2型糖尿病(type 2 diabetes mellitus,T2DM)合并高血压患者认知衰弱的预测价值,并构建风险列线图预测模型。方法 回顾性选取漯河市立医院2024年8月至2025年8月就诊的88例老年T2DM合并高血压患者,根据认知衰弱发生情况分为发生组与未发生组,收集两组患者GDS-15评分、MFS评分、PSQI评分与HbA1c水平,将差异项纳入Logistic回归模型,探究老年T2DM合并高血压患者认知衰弱的相关因素,并构建风险预测模型,评价预测性能。结果 88例老年T2DM合并高血压患者中,26例发生认知衰弱,62例未发生认知衰弱。发生组MFS评分和PSQI评分均显著高于未发生组(均P<0.05),GDS-15评分和HbA1c水平均显著低于未发生组(均P<0.05)。多因素Logistic回归分析结果显示,高MFS评分和高PSQI评分均是老年T2DM合并高血压患者发生认知衰弱的危险因素(均P<0.05),低GDS-15评分与低HbA1c水平均是其保护因素(均P<0.05)。列线图风险预测模型的曲线下面积(area under the curve,AUC)为0.994,表明预测价值较高。结论 GDS-15评分、MFS评分、PSQI评分与HbA1c水平对老年T2DM合并高血压患者发生认知衰弱具有一定预测价值,根据以上因素可及时识别高风险患者,制订相应干预策略。

    Abstract:

    Objective To analyze the predictive value of 15-item geriatric depression scale (GDS-15)-simplified version, morse falls assessment scale (MFS), Pittsburgh sleep quality index (PSQI) and hemoglobin A1c (HbA1c) on cognitive decline in elderly patients with type 2 diabetes mellitus (T2DM) complicated with hypertension, and to construct a risk-line chart prediction model. Methods A total of 88 elderly patients with T2DM complicated with hypertension who attended Luohe Municipal Hospital from August 2024 to August 2025 were retrospectively selected. Based on the occurrence of cognitive impairment, they were divided into an impairment group and a non-impairment group. Data collected for both groups included GDS-15 scores, MFS scores, and PSQI scores, and HbA1c levels. Variables showing significant differences were incorporated into a Logistic regression model to investigate factors associated with cognitive impairment in elderly patients with T2DM and hypertension. A risk prediction model was constructed to evaluate predictive performance. Results Among 88 elderly patients with T2DM complicated with hypertension, 26 experienced cognitive impairment, while 62 did not. The MFS score and PSQI score of the occurrence group were higher than those of the non occurrence group (both P< 0.05), while the GDS-15 score and HbA1c level were lower than those of the non occurrence group (both P<0.05). The results of logistic regression analysis showed that high MFS score and high PSQI score were both risk factors for cognitive impairment in elderly patients with T2DM complicated with hypertension (both P<0.05), low GDS-15 score and low HbA1c level were both protective factors (both P<0.05). The area under the curve (AUC) value of the risk prediction model for the line chart was 0.994, indicated high predictive value. Conclusion GDS-15 score, MFS score, PSQI score, and HbA1c levels demonstrate predictive value for cognitive decline in elderly patients with T2DM complicated with hypertension. These factors enable timely identification of high-risk individuals and the development of corresponding intervention strategies.

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李明月. GDS-15 评分、MFS 评分、PSQI 评分与HbA1c 对老年2 型糖尿病合并高血压患者认知衰弱的预测价值[J].生物医学工程学进展,2026,(3):172-177

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  • 收稿日期:2025-12-13
  • 最后修改日期:2025-12-27
  • 录用日期:2025-12-27
  • 在线发布日期: 2026-08-19
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