Objective To explore the effect of comprehensive management based on the concept of homogeneous medical services on the patient experience and prognosis improvement of patients undergoing surgery for lower extremity varicose veins (LEVV). Methods A total of 100 patients who underwent LEVV surgery at Kaifeng Central Hospital from January 2023 to December 2024 were included and randomly divided into a control group (n＝50, conventional plan) and an intervention group (n＝50, comprehensive management based on the concept of homogeneous medical services). Patient experience was assessed with picker patient experience questionnaire(PPEQ), clinical symptoms with venous clinical severity score(VCSS), and quality of life with chronic venous insufficiency quality of life questionnaire(CIVIQ-20), while postoperative complications were recorded. Results The intervention group had significantly higher PPEQ scores than the control group (P＜0.001), with better scores in all dimensions (all P＜0.001). No significant difference in VCSS was found between the groups (P＞0.05). The intervention group showed higher CIVIQ-20 scores at 1, 3, and 6 months postoperatively (all P＜0.001), with significantly fewer complications at 6 months (P＜0.05). Conclusion Comprehensive management based on homogeneous healthcare services improves the patient experience, quality of life, and reduces postoperative complications in patients undergoing surgery for LEVV, enhancing quality of medical services and prognosis.