ObjectiveTo explore the timing of urethral catheter removal in patients undergoing transurethral resection of bladder tumor (TURBT) surgery .MethodsFrom May 2021 to May 2024, a total of 110 patients who underwent TURBT at Nanyang Central Hospital were enrolled in this study. They were randomly assigned to either a control group or an observation group using a random number table, with 55 patients in each group. In the control group, the urinary catheter was removed according to the routine method from 72 h to 96 h after operation, and in the observation group, the urinary catheter was clamped at 24 h after operation. The pain of micturition, the success of natural micturition and induced micturition in the two groups were recorded, and the time of indwelling catheter, the time from extubation to first micturition, the first micturition volume and adverse reactions in the two groups were recorded.ResultsThe visual analogue scale (VAS) scores in the observation group were lower than those in the control group at the first urination and 1 h after urination (all P＜0.05), the success rate of spontaneous urination was higher than that in the control group (P＜0.05), the first urine output was higher than that in the control group (P＜0.05), the urinary tract infection and urinary retention were lower than those in the control group (all P＜0.05).ConclusionEarly clamping and timely removal of urinary catheter after TURBT surgery can reduce the pain of patients, improve the success rate of natural urination, increase the first urination, and reduce the risk of urinary tract infection and urinary retention.