Objective To explore the clinical effect of TiRobot surgical robot-assisted percutaneous fixation of minimally invasive channel screws in the treatment of pelvic fractures. Methods A total of 82 patients with pelvic fractures were included in this study, all of whom were from Nanyang Nanshi Hospital. The selection period was from May 2022 to May 2024. They were divided into the control group (38 cases, percutaneously fixed minimally invasive channel screws treatment) and the study group (44 cases, TiRobot surgical robot-assisted percutaneous fixation of minimally invasive channel screws treatment) by the random number table method. The clinical indicators of the two groups of patients, the degree of pain at each time point after the operation, the stress index level before and after the operation, the pelvic recovery indicator lever before and after the operation, bone metabolism indicator lever before and after the operation, and the incidence of complications were recorded and analyzed. Results The surgical time, first time out of bed and hospitalization of patients in the study group were shorter than those of the control group, and the number of intraoperative bleeding and screw adjustments were reduced compared with the control group (t=10.024, 21.047, 15.050, 15.005, 12.575, all P<0.05); the visual analog scale (VAS) scores of the study group were lower than those of the control group at 6-72 hours postoperatively (t=3.525, 3.960, 6.228, 10.812, and 6.022, all P <0.05); at 24 hours postoperatively, the level of stress index increased in both groups compared to preoperative levels, and the degree of rise in the study group was lower than that in the control group (t=10.176, 8.593, both P<0.05); at 6 months postoperatively, Harris and BBS scores improved in both groups compared to preoperative scores, with significantly greater improvements in the study group (t=12.958, 3.335, both P<0.05); at 6 months postoperatively, both groups demonstrated greater improvements in all bone metabolism indicators compared to their preoperative levels, with the study group showing significantly higher (t=7.854, 3.159, 3.270, both P<0.05); the total incidence of complications in the study group (4.55%) was significantly lower than that in the control group (28.90%) (χ2=9.101, P<0.05). Conclusion TiRobot surgical robot assisted percutaneous fixation of minimally invasive channel screws in the treatment of pelvic fractures can alleviate patients’ pain, reduce stress response, improve bone metabolism indicators, promote pelvic recovery, and be safer.